Systemic Treatment of Pediatric Psoriasis: A Review
نویسندگان
چکیده
منابع مشابه
Systemic Treatment of Pediatric Psoriasis: A Review
Psoriasis is a chronic, immune-mediated, inflammatory skin disease, affecting 1-3% of the white population. Although the existence of two psoriasis incidence peaks has been suggested (one in adolescence before 20 years of age and another in adulthood), its onset may occur at any age, including childhood and adolescence, in which the incidence is now estimated at 40.8 per 100,000. As for adult p...
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Psoriasis is a chronic inflammatory skin disease, which affects approximately 2.6% of the population in Northern Europe and Scandinavia. In order to achieve disease control, combinations of systemic treatments are sometimes needed for variable time periods. However, no evidence-based guidelines exist for the use of systemic combination therapy. Therefore, our aim was to review the current liter...
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Psoriasis is a multifactorial inflammatory papulosquamous disease affecting 0.5% to 2% of the pediatric population. Pediatric psoriasis, presenting similar to adult psoriasis, significantly reduces patient quality of life, often requiring an individualized treatment approach for each patient. Combination and rotational therapy are helpful in reducing toxicity and maximizing efficacy. Patients w...
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Cyclosporin was isolated in 1970, by Jean François Borel at Sandoz Laboratories (Basel, Switzerland), from the soil fungus Tolypocladium inflatum (Borel et al., 1995; Amor et al., 2010). The compound was initially identified as a possible antifungal agent, but it was subsequently shown to have limited antifungal activity. However, in 1976, the drug demonstrated potent immunosuppressive properti...
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Childhood psoriasis has a significant impact on the child ́s quality of life and those who cannot be managed with topical treatment should be considered for systemic treatment. The majority of systemic therapies used for childhood psoriasis are off-label drug therapies. Evidence-based studies on systemic treatment of childhood psoriasis are scarce, and treatment algorithms are generally based on...
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ژورنال
عنوان ژورنال: Dermatology and Therapy
سال: 2016
ISSN: 2193-8210,2190-9172
DOI: 10.1007/s13555-016-0117-6